It has the chemical name of ,,-Dimethylphenethylamine hydrochloride. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Lomaira: One tablet three times a day, taken 30 minutes before meals. The possibility of an association between valvular heart disease and the use of Phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken Phentermine alone. Nationwide Efforts to Combat the Problem Questions To Discuss At the completion of this block of instruction you will be able to answer the following questions: 1. Because pediatric obesity is a chronic condition requiring long-term treatment, the use of this product, approved for short-term therapy, is not recommended. Another important fact to consider before taking Phentermine is that it should never be used by women who are pregnant or who are currently breastfeeding. Initial U.S. Approval: 1959 -----INDICATIONS AND USAGE----- Suprenza is a sympathomimetic amine anorectic indicated as a short-term adjunct (a few weeks) in a regimen of . What You Should Know Before Taking Phentermine, Frequently Asked Questions About Phentermine, refer to our phentermine drug interactions data, Frequently Asked Questions about phentermine, https://www.drugs.com/ingredient/phentermine.html, http://www.rxlist.com/adipex-p-drug/patient-avoid-while-taking.htm, http://www.everydayhealth.com/drugs/phentermine, https://www.ncbi.nlm.nih.gov/pubmed/27664021, https://www.ncbi.nlm.nih.gov/pubmed/26584649, https://www.ncbi.nlm.nih.gov/pubmed/26446094, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560177/, https://www.ncbi.nlm.nih.gov/pubmed/25911503, Feeling like they are going to faint, often accompanied by chest pain, Fluttering in the patients chest, as well as pounding heartbeats. Each tablet contains the following inactive ingredients: starch, lactose anhydrous, microcrystalline cellulose, colloidal silicon dioxide, stearic acid, magnesium stearate and blue sugar spheres. Concomitant use of alcohol with phentermine may result in an adverse drug reaction. Dr. Lazarus, we will discuss combination phentermine therapy later in this roundtable discussion. It helps patients lose weight by suppressing their appetite and boosting their energy levels, thus leading to a more active lifestyle and greater calorie burn. However, the medication does have a considerable street value. Bariatric doctors are doctors that specialize in weight management. The additional boost in energy will also increase the physical activity levels, thereby providing an additional method for them to lose weight and gain overall health benefits. See DrugAbuse and Dependence (9.3). You may opt-out of email communications at any time by clicking on information highlighted below and resubmit the form. Different brands manufacture, distribute and sell Phentermine drugs. They inhibit the activity of an entire enzyme family known as monoamine oxidase. Phentermine, an amphetamine congener, is the most widely used anti-obesity drug in the U.S. Phentermine hydrochloride: Usual dosage is 8 mg 3 times daily (given 30 minutes before meals) or 15-37.5 mg once daily (in the morning). << /Length 5 0 R /Filter /FlateDecode >> , Since 1997, allnurses is trusted by nurses around the globe. Do not crush, break, or chew it. In some cases, the doctor may prescribe Phentermine in smaller doses and advise the patient to take it up to three times in a single day. 138 0 obj <>stream Existing health conditions that may act as a problem include diabetes, thyroid disorders, hypertension and kidney disease. If we combine this information with your protected PDF What Every Pharmacist Needs to Know About Controlled Substances in Take 1 tablet or capsule once a day before breakfast or 1-2 hours after breakfast. This search engine indexes the Drug Enforcement Administration Diversion Control Program Web Site (www.deadiversion.usdoj.gov) only. PDF Reference ID: 3115694 - Food and Drug Administration Your doctor may prescribe both of these drugs separately, or choose to prescribe Qsymia, which is another medication that combines Phentermine and Topamax. Current Obesity Reports. hWmo8+jE'"m{F Carefully follow the dosing instructions for the form you are using. Losing weight during pregnancy can harm both a mother and her baby. Requirements may be altered [see Warnings and Precautions (5.9)]. The possibility of an association between PPH and the use of Phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who reportedly have taken Phentermine alone. If you miss a dose of this medicine, take it as soon as possible. Phentermine should never be taken after 6 pm in the afternoon as it causes insomnia. It should melt quickly. Sign-up for our weekly newsletter! Ideally, patients should take it on an empty stomach. The natural history of obesity is measured over several years, whereas the studies cited are restricted to a few weeks duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. Review/update the Telehealth Guidance - Ohio W0Qxe {>x??}# cGCSGGC[G(P A@3'i~ (2[n! In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg Phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg Phentermine capsule or a 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of Phentermine. This website is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. OSMA has historically had concerns with the limitations that these rules place on physicians who treat patients with obesity. The following information includes only the average doses of this medicine. Follow your doctor's orders or the directions on the label. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Or it can help you feel full longer. Rx only. U.S. Food and Drug Administration. Below we explain how to get phentermine, including why you need a prescription, who can take this medication, and how to get your doctor to prescribe phentermine. Acidification of the urine increases Phentermine excretion. Children 16 years of age and youngerUse is not recommended. Weight Loss Prescribing Rules Ohio Administrative Code 4731-11-04 and 4731-11-04.1 The medical board is currently reviewing its long-standing rules regarding prescribing controlled substances for the treatment of obesity. The most common brand of Phentermine is a product known as Adipex, but officially called Adipex-P. One should bear in mind that Phentermine is not only a drug to help reduce the baseline body weight of patients, but it also reduces a patients risk of developing certain health diseases. https://fco.factsandcomparisons.com/. Also, it may cause certain side effects to become much worse. privacy practices. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Before writing a phentermine prescription, he or she will evaluate your: While any doctor can prescribe phentermine, not all doctors feel comfortable doing so. https://med.ohio.gov/LinkClick.aspx?fileticket=Q2JmI7o-3HI%3d&portalid=0. It is contraindicated for patients with current or past: cardiovascular disease (heart problems), hyperthyroidism, glaucoma, agitated states, drug/alcohol abuse, or reactions to sympathomimetic amines. Broad St., 3 rd Floor GUIDANCE DOCUMENT: Physician Assistant Prescriptive Authority Effective 10/15/15 The following information is provided as guidance, and may not reference all statutes and rules Sally Cohen holds a degree in nutrition sciences from Alcorn State University. Rule 4731-11-02 | General provisions. See Drug Abuse and Dependence (9) and Overdosage (10). The plasma protein binding decreases as blood topiramate increases. Phentermine may decrease the hypotensive effect of adrenergic neuron blocking drugs. More specifically, this medication is an option for people with a body mass index (BMI): Greater than 30 kg/m2 Greater than 27 kg/m2 + one or more weight-related condition Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. Some weight loss clinics also insist that patients take additional supplements, such as vitamin B12 shots and 5-HTP, to boost phentermine despite the supplements unproven effectiveness. Even patients who are overweight and pregnant at the same time are not allowed to use this product. Phentermine.com is a property of: Careworld LLC. The dosage may be adjusted to the patients need. ): Most people get their phentermine from a family or primary care doctor ( endstream endobj startxref (1) The prescriber shall assess the patient, at a minimum, once in the first three months of utilization of controlled substances for weight reduction, and shall record in the patient record information demonstrating the patient's continuing efforts to lose weight, the patient's dedication to the treatment program and response to treatment, and Safety and effectiveness in pediatric patients have not been established. However, phentermine is not appropriate or safe for everyone. National Association of Boards of Pharmacy. Treatment should be discontinued in patients who develop new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema, and patients should be evaluated for the possible presence of pulmonary hypertension. The State Medical Board of Ohio met on January 13, 2021. Ohio Administrative Code 4731-11-04 and 4731-11-04.1. [Who Prescribed Your Phentermine?]. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Phentermine is not to be used while pregnant or breastfeeding under any circumstances. Phentermine has not been studied in patients with eGFR less than 15 mL/min/1.73m2, including end-stage renal disease requiring dialysis; avoid use in these populations. Swallow the extended-release capsule whole. hbbd``b` @IHpA\> . Adipex-P: Package Insert / Prescribing Information - Drugs.com Studies have not been performed with Phentermine to determine the potential for carcinogenesis, mutagenesis or impairment of fertility. Phentermine is contraindicated during pregnancy because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm. Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, amphetamine (d- and dll-amphetamine). Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. If obesity is impacting your fertility or reproductive health, or if you have a specific condition that affects weight (such as PCOS), your gynecologist may consider prescribing phentermine as a short-term weight management strategy. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. \ Detailed Phentermine dosage information Related/similar drugs Numerous side effects have been linked to the use of Phentermine. It is obvious that these symptoms can make the entire program useless. This study guide will help you focus your time on what's most important. HVMs8WQl eLg*&{dd $_;lm |NggK6,M]gu\.BNB. Phentermine hydrochloride/topiramate. Patients must be informed about the risks of use of Phentermine (including the risks discussed in Warnings and Precautions), about the symptoms of potential adverse reactions and when to contact a physician and/or take other action. Specializes in Med-Surg, Trauma, Ortho, Neuro, Cardiac. It should also not be taken within 14 days after taking an MAO inhibitor. The usual adult dose is one tablet (37.5 mg) daily, as prescribed by the physician, administered before breakfast or 1 to 2 hours after breakfast. In some cases, the use of Phentermine has also led to the development of symptoms that are related to erectile dysfunction. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Phentermine is most commonly prescribed to patients who experience negative health effects to excessive amounts of body weight. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Biliopancreatic diversion with duodenal switch (BPD/DS), Endoscopic Sleeve Gastroplasty (Gastric Sleeve), Biliopancreatic diversion with duodenal switch. include protected health information. Doctors often combined the use of Phentermine with diuretics, thyroid hormone medicines and digitalis. Chapter 4731-11 - Ohio Administrative Code | Ohio Laws Many people live far away from their nearest weight loss clinic, which can make follow-ups complicated. 6 Specializes in NICU, PICU, Transport, L&D, Hospice. The combined drug is approved for long-term use. Burguera B, et al. With more than 4 million prescriptions written in the United States each year, phentermine is an undeniably popular weight loss medication ( Comprehensive review of current and upcoming anti-obesity drugs. The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. information submitted for this request. Yes, you need a prescription for phentermine. He or she may prescribe the medication him/herself if you are an appropriate candidate, or he/she may choose to refer you to a specialist for further evaluation and follow-up. A physician is the only person who can prescribe phentermine. Phentermine is a schedule IV drug that requires a consultation with the doctor and a prescription. Choosing a specialty can be a daunting task and we made it easier. Unfortunately, the answer is no in most cases. One of the most important things to consider is the fact that the drug should never be accompanied by an MAO inhibitor. A doctor that sees you regularly is in a unique position to assess the pros and cons of a phentermine prescription because he/she is familiar with your medical history, as well as other medications, allergies, and weight trends over time. A doctor is the only person who can determine if phentermine is right for you. Phentermine is pregnancy category X, so it should never be taken while pregnant or nursing ( Patients with a larger body weight may need to take a larger dose, depending on whether they have any health concerns that may be worsened by the usage of a larger dose. They help the body produce a larger amount of energy from fat cells, which further reduces body fat percentage. The use of Topamax and Phentermine is actually an FDA-approved combination. Opioid Prescribing Guidelines - Ohio Six years after the approval, a similar drug, called Aminorex, were released in Europe with the same purpose of helping obese individuals. The combined drug is approved for long-term use. The drug has two primary functions in the human body, which is the reason why it is always accompanied by these lifestyle changes. Overdosage of pharmacologically similar compounds has resulted in fatal poisoning usually terminates in convulsions and coma. Dispense in a tight container as defined in the USP, with a child-resistant closure (as required). @ d The initial symptom of PPH is usually dyspnea. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. With respect to the care and treatment of patients with obesity, APRNs are required to incorporate the State Medical Board rules applicable to physicians and prescribing practices. The drug is mainly an appetite suppressant, thus making a patient feel fuller after (and between) meals and making the patient more likely to consume foods that have lower amounts of calories. While these are the most common side effects of the drug, they are not the only consequences associated with the intake of this medication. The drug is always accompanied by increased physical activity and a diet that includes a lower amount of calories. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Contraindications History of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension) During or within 14 days following the administration of monoamine oxidase inhibitors Hyperthyroidism Required fields are marked *. Doctors used it to help patients who experience certain health issues caused by obesity to lose weight and improve the symptoms they are experiencing. Phentermine Hydrochloride Tablets, USP 37.5 mg are white oval shaped bisected tablet with blue specs, debossed with 810 on bisected side. Thus, in order to make the most of this drug, patients need make some effort too. Here are the results of a recent poll that asked current phentermine patients where they received their phentermine prescription ( Facts & Comparisons eAnswers. RPYcn@b[%XYK'Q %[.()GTkJ WCf.-i>n-oIzE*D40f#Gp'LcddmE8;>u?X"tO 1]M={4,ReC8E8Z Q1Lt$-XpFCrTJ Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Phentermine is 17.5% plasma protein-bound, while topiramate is 15 - 41% plasma protein-bound when the blood concentration range is 0.5 to 250 g/mL. Tell patients to keep Phentermine in a safe place to prevent theft, accidental overdose, misuse or abuse. Specializes in Med nurse in med-surg., float, HH, and PDN. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. As a reminder, Ohio law requires physicians who prescribe any controlled substances, not just opioids, to submit an ICD-10 code with that prescription. Phentermine is approved for use for up to 12 weeks. hbbd``b`z$@D`]"@DeX- Bb V ``LA\F*? Please consult with your physician before you make any decisions regarding your health. The possible role of Phentermine in the etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. Some preparations of the formula, however, have been classified as schedule II drugs. This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. PDF Mid-Level Practitioners Authorization by State OhioBWC - Provider: (Opioid Educate) - About prescribing Phentermine is a Schedule IV controlled substance. Phentermine is intended to help overweight and obese patients who have already tried losing weight with diet and exercise. OSMA has historically had concerns with the limitations that these rules place on physicians who treat patients with obesity. In addition to its function as an appetite suppressant, Phentermine drugs also act as energy boosters. Dosage should be individualized to obtain an adequate response with the lowest effective dose. If the time is too close to the next dose, it is recommended to skip the dose they have missed. Phentermine is a Schedule 4 drug. Available for Android and iOS devices. The amount of medicine that you take depends on the strength of the medicine. Your email address will not be published. To provide you with the most relevant and helpful information, and understand which Use caution when administering Phentermine to patients with renal impairment. This is a label given to drugs that can be misused. It is vital to talk with the doctor before using Phentermine with other products. Highlighted below are the topics discussed at the meeting that OSMA is closely following. information highlighted below and resubmit the form. Phentermine doctors network. In some cases, the use of this drug in combination with other pills may cause the effects of other drugs to increase. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. The prescribing designation for anorexiants can be located on page 15 of The Formulary Developed by the Committee on Prescriptive Governance (The Formulary). In order to determine the effectiveness of certain pharmaceuticals, supplements and other substances, clinical trials and scientific research are often conducted among a group of volunteers. hb``````>X,K10wdjdZ(`l Ro4' b2h>$:-9.AKL1}c$vEP;-@c=en`Y %YQh` &^ However, it caused a chronic condition known as pulmonary hypertension, which led to the death of many patients. If you are a Mayo Clinic patient, this could It is illegal and unsafe to buy phentermine without a prescription. There are reports of patients who have increased the dosage of these drugs to many times than recommended. Primary Pulmonary Hypertension (PPH) a rare, frequently fatal disease of the lungs has been reported to occur in patients receiving a combination of Phentermine with fenfluramine or dexfenfluramine. 3 The usual duration of treatment is 12 weeks or less. Obesity pillars roundtable: Phentermine - Past, present, and future The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The limited usefulness of agents of this class, including Phentermine, [see Clinical Pharmacology (12.1, 12.2)] should be measured against possible risk factors inherent in their use such as those described below. Manifestations of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states. Place the tablet on the top of your tongue right after removing it from the bottle. (phentermine hydrochloride) orally disintegrating tablet C IV . It is illegal & unsafe to buy phentermine online consider Phen Caps instead! The drug is classified under a certain chemical class known as amphetamine as it has a similar pharmacology value to other drugs classified in the class. I am finding limited information. The drug is usually prescribed at the lowest possible dose to new users, which is 15mg per day. So some health care providers might order it for longer use. the unsubscribe link in the e-mail. Apart from not combining Phentermine with the MAO inhibitors, a patient should also first ensure they are not allergic to Phentermine before they take it. Rule 4731-11-04 | Controlled substances: Utilization of short term anorexiants for weight reduction. While suffering from any of these health concerns may be a cause for concern, it does not mean a patient will not be able to use Phentermine at all. Management of acute Phentermine hydrochloride intoxication is largely symptomatic and includes lavage and sedation with a barbiturate.